Effect of alkalinization of lidocaine on median nerve block

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Effect of alkalinization of lidocaine on median nerve block.

Median nerve blocks were performed in 10 volunteers in a randomized, double-blind, crossover study to compare the effects of 1% plain lidocaine with 1% lidocaine in sodium bicarbonate 0.1 mmol litre-1. Sensations of hot, cold, pinprick and light touch, compound motor and sensory nerve action potentials, and skin temperature were assessed at 2-min intervals. pH was 6.4 +/- 0.1 for plain lidocain...

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Lidocaine Alkalinization with Borate Buffer: Evaluation of Onset and Duration Time of Analgesia in Peripheral Nerve Block in Rat

Objective: Evaluation of onset and duration of peripheral nerve blockage with alkalinized lidocaine by borate buffer instead of sodium bicarbonate. Study design: Experimental randomized cross-over study. Animals: Forty male Sprague-Dawley rats (body weight 200–300 g) were used in this study. Methods: Four 1.0% lidocaine solutions were prepared from commercially available solutions. The treat...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2000

ISSN: 0007-0912

DOI: 10.1093/oxfordjournals.bja.a013397